Taste Mask Orodispersible Tablet of Metronidazole: Development and...

Description: Taste Mask Orodispersible Tablet of Metronidazole: Development and Characterization of taste mask Orodispersible tablets of Metronidazole Paperback – March 22, 2012 Product Details Publisher : LAP LAMBERT Academic Publishing (March 22, 2012) Language : English Paperback : 88 pages Item Weight : 5 ounces Dimensions : 5.91 x 0.2 x 8.66 inches Patients who have problems in swallowing encounter difficulties in taking tablets, particularly pediatric and geriatric patients. Such problems can be resolved by means of orodispersible tablets. These tablets disintegrate instantaneously when put on tongue, releasing the drug that dissolves or disperses in the saliva.Metronidazole is active against a wide variety of anaerobic protozoal parasites and anaerobic present study aim to prepare tablets that can rapidly disintegrate in oral cavity (orodispersible), another challenge with this model drug is to mask the bitter taste. Taste masking was achieved by using aminoalkyl methacrylate copolymer (Eudragit E-100) in the different ratio (1:2 and 1:3) by extrusion technique. The IR shows that there was no significant evidence for interaction between drug and polymers. Six formulations were prepared using taste masked granules and different disintegrants (LH-11) and Avicel PH-102 by varying concentration. Read more

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Number of Pages: 88 Pages

Publication Name: Taste Mask Orodispersible Tablet of Metronidazole

Language: English

Publisher: LAP Gmbh & Company KG

Publication Year: 2012

Subject: Pharmacology

Item Height: 0.2 in

Item Weight: 5 Oz

Type: Textbook

Author: Aditya Nath Pandey, Anupam Jain, Suresh Kumar Sahu

Subject Area: Medical

Item Length: 9 in

Item Width: 6 in

Format: Trade Paperback