Description: Pathogen-Host Interactions: Antigenic Variation v. Somatic Adaptations Please note: this item is printed on demand and will take extra time before it can be dispatched to you (up to 20 working days). Author(s): Ellen Hsu, Louis Du Pasquier Format: Hardback Publisher: Springer International Publishing AG, Switzerland Imprint: Springer International Publishing AG ISBN-13: 9783319208183, 978-3319208183 Synopsis This volume provides in-depth reviews of model systems that exemplify the arms race in host-pathogen interactions. Somatic adaptations are responsible for the individualization of biological responses to the environment, and the continual struggle between host immune systems and invading pathogens has given rise to corresponding processes that produce molecular variation. Whether in mollusks or human beings, various host somatic mechanisms have evolved independently, providing responses to counter rapidly-changing pathogens. The pathways they utilize can include non-heritable changes involving RNA and post-translational modifications, or changes that produce somatic DNA recombination and mutation. For infectious organisms such as protozoans and flatworms, antigenic variation is central to their survival strategy. Evolving the ability to evade the host immune system not only increases their chances of survival but is also necessary for successful re-infection within the host population.
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Book Title: Pathogen-Host Interactions: Antigenic Variation v. Somatic Ada...
Item Height: 235 mm
Item Width: 155 mm
Series: Results and Problems in Cell Differentiation
Author: Ellen Hsu, Louis Du Pasquier
Publication Name: Pathogen-Host Interactions: Antigenic Variation V. Somatic Adaptations
Format: Hardcover
Language: English
Publisher: Springer International Publishing A&G
Subject: Medicine, Biology
Publication Year: 2015
Type: Textbook
Item Weight: 6387 g
Number of Pages: 336 Pages
