Metabotropic Glutamate Receptors in Psychiatric and Neurological Disorders by Lo

Description: Metabotropic Glutamate Receptors in Psychiatric and Neurological Disorders by Lori Knackstedt, Marek Schwendt Metabotropic Glutamate Receptors in Psychiatric and Neurological Disorders, Volume 168 in the International Review of Neurobiology series, highlights advances in the field, with this new volume presenting interesting chapters on topics such as mGlu receptors in Parkinsons disease, Metabotropic glutamate receptors in estradiol-mediated motivated behaviors in females, mGlu regulation of sleep, Implications for sleep disruptions in psychiatric disorders, Mechanisms of mGlu receptor trafficking; alterations by methamphetamine, Group I mGlu and cocaine seeking, The role of mGlu receptors in fear and anxiety, Regulation of Alcohol Consumption, Reward, Dependence, and Perception by Metabotropic Glutamate Receptor Signaling, and mGlu5 as a biomarker for psychiatric disorders. FORMAT Hardcover LANGUAGE English CONDITION Brand New Author Biography Prof. Lori Knackstedt has a long-standing interest in studying the pathological changes in brain and behavior which occur in response to addictive drugs. For the past nine years, her work has focused on identifying neuroadaptations in the glutamate neurotransmitter system produced by chronic self-administration of addictive drugs such as nicotine, alcohol and cocaine. She then target these neuroadaptations with translational compounds to reduce drug-seeking. To that end, her research involves assessing brain changes in reward circuitry following self- administration of addictive drugs using western blotting, immunohistochemistry, and microdialysis.Prof. Knackstedt began her independent research career as a Research Assistant Professor at the Medical University of South Carolina in 2009. In Fall 2012, she began a tenure-track position in the Psychology Department at UF, where she now run the Neurobiology of Addiction Research Lab. She supervises three graduate students, one post-doctoral fellow and 7 undergraduates. Dr. Schwendt is an Assistant Professor in the Department of Psychology at the University of Florida, Gainesville, FL. His research focuses on psychostimulant induced neuroplasticity underlying persistent drug-seeking and cognitive impairments.Dr. Schwendt completed his M.S. in Comenius University, Bratislava, Slovakia, and his Ph.D. in the Institute of Exp. Endocrinology & University of P.J. Safarik, Bratislava, Slovakia. He completed his Postdoctoral Fellowship in the Medical University of South Carolina, Charleston, SCDr. Schwendt is interested in what causes drug addiction to be a chronic relapsing disorder. He is interested in identifying cellular and molecular mechanisms underlying relapse and drug-induced cognitive deficits which persist well into abstinence. His research utilizes an animal model with high-face validity for human addiction: operant drug self-administration in combination with tasks designed to test memory performance in animals. In particular, his research attempts to elucidate the role of modulatory proteins that fine-tune synaptic transmission during development of drug-induced neural plasticity, and further, to investigate whether in vivo manipulation of these proteins can attenuate or reverse drug-seeking and drug-induced cognitive deficits. Dr. Schwendt believes that characterization of the molecular underpinnings of the long-lasting behavioral consequences of repeated drug administration will provide critical insight into the psychopathology of drug addiction and related psychiatric disorders (including schizophrenia and depression). Table of Contents 1. mGlu receptors in Parkinsons disease2. Metabotropic glutamate receptors in estradiol-mediated motivated behaviors in females3. mGlu regulation of sleep, and implications for sleep disruptions in psychiatric disorders4. Mechanisms of mGlu receptor trafficking; alterations by methamphetamine5. Group I mGlu and cocaine seeking6. The role of mGlu receptors in fear and anxiety7. Regulation of Alcohol Consumption, Reward, Dependence, and Perception by Metabotropic Glutamate Receptor Signaling8. mGlu5 as a biomarker for psychiatric disorders Review "...comprehensively covers the role of metabotropic glutamate receptors (mGluRs), a big group of G protein-coupled receptors, in psychiatric and neurological conditions,... intended for a wide range of scientists in the field of neurological and psychiatric disorders, mainly focusing on molecular mechanisms and effects in disease models.... [C]overs recent advances on the role of mGluRs in neurobehavioral disorders, as in stress, fear, and anxiety-like behaviorals, in addiction, and in sex differences in receptor regulation.... [A] great emphasis has been given on the role of mGluRs in Parkinsons disease, [and] in some neurological conditions, including epilepsy and Alzheimers disease.... The book is of great quality and the content is relevant to neuroscience." -- ©Doodys Review Service, 2024, Anna P Andreou, PhD (Kings College London) Feature Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in International Review of Neurobiology serials Updated release includes the latest information on metabotropic glutamate receptors in psychiatric and neurological disorders Details ISBN032399394X Publisher Elsevier Science & Technology Series International Review of Neurobiology Language English Year 2023 ISBN-10 032399394X ISBN-13 9780323993944 Format Hardcover Series Number 168 Imprint Academic Press Inc Place of Publication Oxford Country of Publication United Kingdom Author Marek Schwendt Pages 430 Publication Date 2023-02-01 UK Release Date 2023-02-01 Alternative 9780323993951 DEWEY 616.8914 Audience Professional & Vocational NZ Release Date 2023-01-31 AU Release Date 2023-01-31 We've got this At The Nile, if you're looking for it, we've got it. With fast shipping, low prices, friendly service and well over a million items - you're bound to find what you want, at a price you'll love! TheNile_Item_ID:158523792;

Price: 460.65 AUD

Location: Melbourne

End Time: 2025-02-10T03:13:41.000Z

Shipping Cost: 0 AUD