Description: Further DetailsTitle: Protein-protein Complexes: Analysis, Modeling And Drug DesignCondition: NewEAN: 9781848163393ISBN: 9781848163393Publisher: Imperial College PressFormat: PaperbackRelease Date: 05/10/2010Description: Given the immense progress achieved in elucidating protein-protein complex structures and in the field of protein interaction modeling, there is great demand for a book that gives interested researchers/students a comprehensive overview of the field. This book does just that. It focuses on what can be learned about protein-protein interactions from the analysis of protein-protein complex structures and interfaces. What are the driving forces for protein-protein association? How can we extract the mechanism of specific recognition from studying protein-protein interfaces? How can this knowledge be used to predict and design protein-protein interactions (interaction regions and complex structures)? What methods are currently employed to design protein-protein interactions, and how can we influence protein-protein interactions by mutagenesis and small-molecule drugs or peptide mimetics?The book consists of about 15 review chapters, written by experts, on the characterization of protein-protein interfaces, structure determination of protein complexes (by NMR and X-ray), theory of protein-protein binding, dynamics of protein interfaces, bioinformatics methods to predict interaction regions, and prediction of protein-protein complex structures (docking and homology modeling of complexes, etc.) and design of protein-protein interactions. It serves as a bridge between studying/analyzing protein-protein complex structures (interfaces), predicting interactions, and influencing/designing interactions.Language: EnglishCountry/Region of Manufacture: GBContributor: Martin Zacharias (Edited by)Author: Martin ZachariasGenre: Science Nature & MathRelease Year: 2010 Missing Information?Please contact us if any details are missing and where possible we will add the information to our listing.
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Publication Name: Protein-protein Complexes: Analysis, Modeling And Drug Design
Title: Protein-protein Complexes: Analysis, Modeling And Drug Design
EAN: 9781848163393
ISBN: 9781848163393
Release Date: 05/10/2010
Release Year: 2010
Country/Region of Manufacture: GB
Contributor: Martin Zacharias (Edited by)
Publisher: Imperial College Press
Publication Year: 2010
Topic: Life Sciences / Molecular Biology, Life Sciences / Biochemistry, Life Sciences / Biophysics, Chemistry / Physical & Theoretical
Book Title: Protein-Protein Complexes : Analysis, Modeling and Drug Design
Number of Pages: 400 Pages
Language: English
Illustrator: Yes
Genre: Science
Item Weight: 0 Oz
Author: Martin Zacharias
Format: Trade Paperback