Description: Human Airway Inflammation : Sampling Techniques and Analytical Protocols, Paperback by Rogers, Duncan F. (EDT); Donnelly, Louise E. (EDT), ISBN 1489943722, ISBN-13 9781489943729, Brand New, Free shipping in the US Rubor (redness), tumor (swelling), calor (heat), and dolor (pain) are the classical signs of inflammation. These features are obvious in the skin, where injury or disease causes flare, wheal, and painful burning sensations. Vasodi- tation underlies the flare and heat, plasma exudation the swelling, and acti- tion of sensory nerves relays pain. In chronic conditions, skin biopsies show inflammatory cell infiltrate. Inflammation is not unique to the skin and contr- utes to disease and repair processes in other organ systems in the body. From the viewpoint of this volume, lung inflammation is now recognized as central to the pathophysiology of a number of severe respiratory conditions, the two most common being asthma and chronic obstructive pulmonary disease (COPD). In asthma, and to a lesser extent COPD, there is evidence of vasodilatation, with congestion of blood vessels accompanied by reddening of the airway mucosa, and of plasma exudation, leading to swelling of the airway wall. Similarly, although less pronounced than in the skin, there is evidence of pain, for example, the - pleasant chest sensations associated with asthma attacks. Understanding the pat- genesis of airway inflammation will enable rational design of drugs to effectively treat conditions such as asthma and COPD. However, whereas immediate access to the skin facilitates investigation of disease processes, the lung, although “open to atmosphere,” is much less accessible. Consequently, the investigation of lung inflammation is usually indirect. Thus, a wide variety of research techniques are used.
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Book Title: Human Airway Inflammation : Sampling Techniques and Analytical Pr
Number of Pages: Xv, 440 Pages
Language: English
Publication Name: Human Airway Inflammation : Sampling Techniques and Analytical Protocols
Publisher: Humana Press
Subject: Pulmonary & Thoracic Medicine
Publication Year: 2013
Type: Textbook
Item Weight: 23.6 Oz
Subject Area: Medical
Item Length: 9 in
Author: Louise E. Donnelly
Item Width: 6 in
Series: Methods in Molecular Medicine Ser.
Format: Trade Paperback
